I am unsure what you are asking, based on the question and the thread title.
The bank may release you from liability on the note. But if you are paying your sister separately, the bank can certainly refuse to release you from the loan as they receive no consideration.
If the bank is asking you to give up separate rights you may have against your sister that involve the property, but not necessarily the loan, no, that isn't advice they should give.
Complete whatever transfer you do through your attorney to best protect your interests.